BAC介导的转FSHα/β基因猪的初步分子鉴定、理化指标测定及生物安全评价

来源 :第九次全国动物生物技术学术研讨会 | 被引量 : 0次 | 上传用户:wuliaoaiaia
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  促卵泡激素(Follicle-stimulating hormone,FSH)是雌雄动物体内很重要的一种生殖激素。中国农业大学的早期研究发现FSHβ基因是影响猪产仔数的主效基因之一;导入二花脸猪FSHα/β基因的转基因小鼠模型证实了该基因能提高产仔数。我们通过体细胞核移植技术将包含二花脸猪FSHα/β基因的细菌人工染色体(BAC)导入大白猪中,以期提高大白猪的繁殖性能。本研究以前期获得的3头转二花脸FSHα/β基因原代大白公猪及其扩繁后代为研究对象,开展了初步的分子鉴定、理化指标测定及生物安全评价工作。
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