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  5. Silica nanoparticles induce oxidative stress,inflammation and endothelial dysfunction viaactivation

Silica nanoparticles induce oxidative stress,inflammation and endothelial dysfunction viaactivation

来源 :全国卫生毒理学术研讨会 | 被引量 : 0次 | 上传用户：bjzcha
【摘 要】
：
Despite the widespread application of silica nanopartieles (SiNPs) in industrial,commercial,and biomedical fields,their response to human cells has not been fully elucidated.Overall,little is known ab
【作 者】
：
Caixia Guo Yinye Xia Piye Niu Lizhen Jiang Junchao Duan Yang Yu Xianqing Zhou Yanbo Li Zhiwei Sun 
【机 构】
：
School of Public Health,Capital Medical University,Beijing,100069,P.R.China;Beijing Key Laboratory o
【出 处】
：
全国卫生毒理学术研讨会
【发表日期】
：
2014年9期
【关键词】
：
silica nanoparticle endothelium oxidative stress Nrf2 MAPK NF-κB 
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　　Despite the widespread application of silica nanopartieles (SiNPs) in industrial,commercial,and biomedical fields,their response to human cells has not been fully elucidated.Overall,little is known about the toxicological effects of SiNPs on the cardiovascular system.In this study,SiNPs with a 58 nm diameter were used to study their interaction with human umbilical vein endothelial cells,HUVECs.
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