Cell-penetrating peptides (CPPs),comprised of short cationic or amphipathic peptides,have the ability to enhance the cellular internalization of polymer nanoparticles via phagocytosis and pinocytosis[
Polyion complex (PIC) micelles as protein delivery carriers have attracted considerable attention in the past decades[1].The protein molecules can be encapsulated into PIC micelles with high loading e
Many types of materials have been used to prepare nanoparticles for drug delivery.Among these materials,proteins are regarded as a good candidate due to their low toxicity,good biocompatibility and pe
Transcutaneous immunization (TCI) is a novel vaccination method that exhibits a great potential for increasing efficiency and compliance of vaccination programs[1].
Gelatin is a good capsule material and has been used widely in the food and pharmaceutical industries.Starch also has a large potential for capsule material and shows a slower drug release behavior.
Hydrogel-based drug delivery systems provide a high-dose and constant release of therapeutic agents in pathological lesion and can avoid non-specific drug distribution in heathy tissues which can sign
Polycationic gene delivery system was widely used for cancer therapy.Polycations with high positive potentials exhibited good transfection efficiency,but at the same time,the surplus positive charges
Temperature and pH value are two significant parameters to assess ones physical health.Significant efforts have been devoted to the development of therapeutic systems based on thermo/pH stimuli[1,2].
Macrophages,ubiquitous phagocytic cells in the human immune system,play a key role in homeostatic,immunological,and inflammatory processes.They are rapidly recruited to the diseased site by signaling
Corneal disease is the main cause of blindness and keratoplasty is the only widely accepted treatment.Due to the shortage of donor tissue,researchers had focused on the research and development of mat