【摘 要】
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Tenderness constitutes one of the main characteristics in beef quality.In this study, a methylome analysis was performed in closed Wye Angus steers with genetically homogenous phenotypic backgrounds.T
【机 构】
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College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China;Departm
【出 处】
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2015第三届中国肉牛选育改良与产业发展国际研讨会
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Tenderness constitutes one of the main characteristics in beef quality.In this study, a methylome analysis was performed in closed Wye Angus steers with genetically homogenous phenotypic backgrounds.Through the use of the Methyl CpG Binding Domain protein-enriched genome sequencing (MBD) method,differentially methylated regions (DMRs) were identified and annotated, respectively.Among 1,576 identified DMRs, 983 were downregulated and 593 were upregulated in the "tender" group, demonstrating a global decrease in DNA methylation.We then depicted the DNA methylation profiles in each chromosome, functional regions of genes, etc.The results from the research provide new insights to the epigenetic factors affecting beef quality.
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