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本文报告1例骨髓移植(BMT)的供者,以预先循环采取及回输自身血作准备,在硬膜外麻醉下自双侧髂后上棘大量抽取骨髓(BM)。经观察认为循环采取及回输自身血不仅在大量抽取BM时起到扩充血容量的作用,还有刺激造血的作用,使能取得较好质量的BM。结果还表明抽取BM后除抽髓局部的BM及GM-CFU产率于抽取BM后1个月时尚未完全恢复外,其血象、免疫学指标及局部压疼等均很快恢复。对BM的恢复情况尚需继续观察。
This article reports a donor of bone marrow transplant (BMT) who was prepared by pre-cycle taking and returning autologous blood and extensively extracting bone marrow (BM) from bilateral posterior superior iliac spine under epidural anesthesia. It has been observed that circulating and taking back blood itself not only plays a role of expanding blood volume when extracting a large amount of BM, but also stimulates hematopoietic cells to achieve better quality BM. The results also show that after the extraction of BM, except for the local BM and GM-CFU, the rate of recovery was not recovered completely at 1 month after BM was extracted, and the hemogram, immunological indexes and local pressure pain were quickly recovered. The recovery of BM need to continue to observe.