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本研究应用半定量逆转录 聚合酶链反应 (ＲＴ ＰＣＲ)和ＤＮＡ印迹技术 ,探讨了 32例急性白血病 (ＡＬ)患儿ｂｃｌ 2和ｂａｘｍＲＮＡ表达及其比值对ＡＬ发病、治疗和预后的临床意义。对象32例ＡＬ ,年龄 1～ 14岁。急性淋巴细胞白血病 (ＡＬＬ) 2 2例 ,急性非淋巴细胞白血病 (
In this study, the clinical significance of bcl-2 and bax mRNA expression and its ratio in AL children with onset, treatment and prognosis of AL was investigated in 32 children with acute leukemia (AL) by semi-quantitative reverse transcription polymerase chain reaction (RT PCR) and Southern blotting. 32 cases of AL, aged 1 to 14 years old. Acute lymphoblastic leukemia (ALL) 2 2 cases, acute non-lymphocytic leukemia (