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灼口综合征是以舌部为主要发病部位、以烧灼样疼痛为主要表现的一组综合征,常不伴有明显的临床损害体征,多发生于更年期前后妇女,这种慢性疼痛性疾病与多水平的神经通路病变、精神心理因素、机体激素及相关分子水平变化、局部刺激及系统性疾病等多重因素相关,其中神经及精神因素占有突出地位。本文主要就神经病变及精神心理因素在灼口综合征发病中的作用作一综述。
Burning mouth syndrome is the tongue as the main site of the disease, with burning pain as the main manifestation of a syndrome, often without obvious signs of clinical damage, and more occurred in menopausal women before and after the chronic pain and disease Multiple levels of neural pathological changes, mental and psychological factors, changes in body hormones and related molecular levels, local irritation and systemic diseases and other multiple factors, of which neurological and mental factors occupy a prominent position. This article mainly reviews the role of neuropathy and psychosocial factors in the pathogenesis of burning mouth syndrome.