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目的观察长期综合社区干预措施对糖耐量减退(IGT)人群的转归及糖尿病高危因素指标的影响,探讨糖尿病防治新模式。方法对上海市某社区居民进行静脉血糖检测,筛选出200例IGT者,并随机分为干预组和对照组,每组100例,对干预组进行为期3年的社区干预,比较2组人群在干预前、后的空腹血糖(FBG)、餐后2h血糖(2hPG)、空腹血清胰岛素(FIns)、餐后2h血清胰岛素(2hIns)、总胆固醇(Tch)、甘油三酯(TG)和身高、体重、腰围、臀围的变化。结果3年社区干预后,干预组在干预前、后的FBG、2hPG、FIns、2hIns、Tch、TG及体重、腰围、臀围的变化及转归与对照组相比,差异均具有统计学意义。结论对IGT人群采取长期综合社区干预措施可明显降低糖尿病高危因素指标,并改善其转归。
Objective To observe the effects of long-term comprehensive community intervention on the outcome of IGT population and the risk factors of diabetes mellitus, and to explore a new mode of diabetes prevention and treatment. Methods Venous blood glucose was detected in a community resident in Shanghai. 200 IGT patients were screened and randomly divided into intervention group and control group, with 100 cases in each group. Community intervention was conducted for 3 years in intervention group. Fasting blood glucose (FBG), postprandial 2h blood glucose (2hPG), fasting serum insulin (FIns), postprandial 2h insulin, total cholesterol (Tch), triglyceride (TG) Weight, waist circumference, hip circumference changes. Results After 3 years of community intervention, the changes of FBG, 2hPG, FIns, 2hIns, Tch, TG, body weight, waist circumference and hip circumference in the intervention group before and after intervention were significantly different from those in the control group . Conclusion Long-term comprehensive community interventions for IGT patients can significantly reduce the risk factors for diabetes and improve their outcomes.