非瓣膜房颤动脉合并血栓栓塞事件,特别是脑卒中的发生率逐年增加,有较高的致死致残率,严重影响到患者的生命和生活质量。本文对房颤的相关因素及华法林抗凝治疗的重要性、治疗现状、抗凝强度的确定进行综述分析,为临床治疗非瓣膜房颤、评定其远期预后提供依据。 Non-valvular atrial fibrillation with thromboembolic events, especially the incidence of stroke increased year by year, have a higher mortality rate caused by death, seriously affecting the patient’s life and quality of life. In this paper, the related factors of atrial fibrillation and the importance of warfarin anticoagulation therapy, the status of treatment and the determination of anticoagulant strength are reviewed and analyzed, which provides the basis for clinical treatment of non-valvular atrial fibrillation and assessment of its long-term prognosis.