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目的 :本实验通过对实验犬使用敷脐镇吐膏和晕海宁片而进行的自身对照研究 ,观察敷脐镇吐膏治疗晕动病的疗效。方法 :对实验犬分别在不同时期使用敷脐镇吐膏 (观察组 )或晕海宁片 (对照组 )后 ,用相同的旋转刺激量诱导犬流涎或呕吐 ,测定并比较诱导流涎或呕吐的时长以分别评价观察组与对照组对相同刺激量的耐受性 ,从而客观比较两种药物的疗效。结果 :观察组对相同刺激量的耐受时间较对照组明显延长 ,两组比较差异有极显著性 (P<0 .0 1)。结论 :敷脐镇吐膏对晕动病的治疗作用明显优于晕海宁片。
Objective : This experiment was conducted through self-control study of experimental dogs using Fu Nang Zhen Tuo Gao and Hai Ha Ning Tablets to observe the effect of Fu Nang Zhen Tuo Pao in the treatment of motion sickness. METHODS: Dogs were induced to shed or vomit with the same amount of rotational stimuli, and the duration of induction of salivation or vomiting was measured and compared between experimental dogs using Fu Nian Zhen Tuo (Observation group) or Ha Hai Ning (Control group) at different times. To evaluate the tolerance of the same stimuli in the observation group and the control group, respectively, to objectively compare the efficacy of the two drugs. Results: The tolerance time of the observation group to the same stimulus was significantly longer than that of the control group. The difference between the two groups was extremely significant (P<0.01). Conclusion: The therapeutic effect of Fu Nian Zhen Tuo on motion sickness is better than that of Yun Haining Tablets.