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目的了解精神病住院患者甲型肝炎病毒(HAV)、乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)感染状况,为精神病患者病毒性肝炎的临床防治提供参考。方法收集2010年1月-2016年6月期间洛阳荣康医院住院治疗的1 874例精神病患者临床资料,对其抗HAV-IgM、HBV表面抗原(HBsAg)、抗HCV检测结果进行统计分析。结果 331例患者检测出抗HAV-IgM、HBsAg、抗HCV阳性,感染率为17.66%,抗HAV-IgM、HBsAg、抗HCV阳性患者分别有18例、324例、11例,HAV、HBV、HCV感染率分别为0.96%、17.28%、0.59%。单一抗HAV-IgM、HBsAg、抗HCV阳性患者分别有4例、308例、3例,抗HAV-IgM+HBsAg阳性、抗HAV-IgM+抗HCV阳性、HbsAg+抗HCV阳性、抗HAV-IgM+HbsAg+抗HCV阳性患者分别为10例、2例、4例、2例,构成比分别为1.21%、93.05%、0.91%、3.02%、0.60%、1.21%、0.60%;病毒性肝炎(HAV、HBV、HCV)病毒感染率女性、有流浪史患者分别为20.27%、22.63%,高于男性、无流浪史者15.68%、16.61%,年龄21~岁、31~岁者感染率分别为23.58%、28.70%,高于其他年龄段患者,差异均有统计学意义(P<0.05),不同类别精神病患者之间感染率比较差异无统计学意义(P>0.05)。结论该院住院精神病患者HBV感染率相对较高,HAV及HCV感染率相对较低,以单一感染为主,女性、有流浪史的年轻患者病毒性肝炎感染状况更为恶劣,精神病患者病毒性肝炎危害应当提升到公共卫生健康问题加以重视,为该人群提供更多病毒性肝炎防控措施。
Objective To understand the status of Hepatitis A virus (HAV), Hepatitis B virus (HBV) and Hepatitis C virus (HCV) inpatients with mental illness and to provide reference for clinical prevention and treatment of viral hepatitis in psychiatric patients. Methods The clinical data of 1 874 psychiatric patients hospitalized in Rongyang Hospital of Luoyang from January 2010 to June 2016 were collected and their anti-HAV-IgM, anti-HBsAg and anti-HCV test results were statistically analyzed. Results 331 patients were detected positive for anti-HAV-IgM, HBsAg and anti-HCV, the infection rate was 17.66%. There were 18 cases, 324 cases and 11 cases of anti-HAV-IgM, HBsAg, The infection rates were 0.96%, 17.28% and 0.59% respectively. HAV-IgM + anti-HCV positive, HbsAg + anti-HCV positive, anti-HAV-IgM + HbsAg + The anti-HCV positive patients were 10 cases, 2 cases, 4 cases and 2 cases respectively. The constituent ratios were 1.21%, 93.05%, 0.91%, 3.02%, 0.60%, 1.21% and 0.60% , HCV) were 20.27% and 22.63% respectively in women and those with stray history, which were 15.68% and 16.61% higher than those in male and without stray history, respectively. The infection rates of patients aged 21 to 31 years old were 23.58% 28.70%, higher than those in other age groups, the difference was statistically significant (P <0.05). There was no significant difference in the infection rates among different psychiatric patients (P> 0.05). Conclusions Inpatients with psychosis have a relatively higher rate of HBV infection and relatively lower infection rates of HAV and HCV, with single infection as the mainstay. Female patients with viral vaginosis are more likely to suffer from viral hepatitis in young patients with stray history. Harm should be promoted to public health and health issues to be taken seriously, for the population to provide more viral hepatitis prevention and control measures.