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本文报道,在制备好的成纤维细胞培养物中,溴脱氧尿核苷(BrdU)有效的诱发R-型复制以证明fra(X)(q27)脆性位点。该方法包括用氟脱氧尿核苷(FdU)抑制G_1/S的转换就进行部分同步培养。这种
Here we report that bromodeoxyuridine (BrdU) effectively induced R-type replication in the prepared fibroblast cultures to demonstrate the fra (X) (q27) fragile locus. The method includes partial synchronous culture with fluorodeoxyuridine (FdU) inhibiting G 1 / S conversion. This