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目的：正确评价国产重组人生长激素（r-hGH）对促进生长激素缺乏症（GHD）儿童身高增长作用的疗效和安全性，观察相关血清生化指标的变化。方法：选择GHD患儿9例，给予国产r－hGH0.1IU／kg·d，疗程6个月。结果：治疗后生长速度由（2．66±1．07）cm／年增至（12．62±4．32）cm／年（疗程3个月时），（12.53±3．86）cm／年（疗程6个月时）（P＜0．01）；完全性GHD疗程优于部分性GHD。结论：国产r－hGH治疗GHD近期疗效肯定，而且安全可靠。
Objective: To evaluate the efficacy and safety of domestic recombinant human growth hormone (r-hGH) on the growth of children with growth hormone deficiency (GHD), and to observe the changes of related serum biochemical indexes. Methods: Nine children with GHD were selected and given domestic r-hGH 0.1 IU / kg · d for 6 months. Results: After treatment, the growth rate increased from (2.66 ± 1.07) cm / year to (12.62 ± 4.32) cm / year (3 months after treatment), (12.53 ± 3.86) cm / Year (6 months) (P <0.01); complete GHD treatment is superior to partial GHD. Conclusion: Domestic r-hGH treatment of GHD positive effect, and safe and reliable.