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研究临床论著中统计学缺陷是了解和评价临床科研论著质量的重要途径[1]。当前，一些国际著名医学杂志和重要的专业期刊，均定期报道其出版的论著中统计学应用状况，在医学界已产生了一定的影响[2]。类似报道国内尚少见。因此，我们对1992年7月～1993年6月出版的12期《中华内科
The study of statistical defects in clinical work is an important way to understand and evaluate the quality of clinical research work [1]. At present, some international famous medical journals and important professional journals regularly report the statistical applications of their publications, which has had a certain influence in the medical community [2]. Similar domestic reports are rare. Therefore, we have published 12 issues of Chinese Internal Medicine from July 1992 to June 1993.