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目的：评价中药加高渗腹透液及单纯高渗腹透液灌肠治疗慢性肾功能衰竭（ＣＲＦ）尿毒症期患者的疗效。方法：６１例患者随机分为２组。治疗组用中药加４．２５％Ｂ５１８５高渗腹透液灌肠，对照组单纯应用４．２５％Ｂ５１８５高渗腹透液灌肠，每次３００ｍｌ，每日２次，每次保留２小时以上。结果：治疗组总有效率８８．５７％，对照组总有效率８０．７７％，２组比较无显著性差异（Ｐ＞０．０５）。２组治疗后血尿素氮、肌酐和肌酐清除率均有明显改善（Ｐ均＜０．０５）。结论：中药加高渗腹透液灌肠或单纯高渗腹透液灌肠，均为治疗ＣＲＦ尿毒症期的有效药物。此方法操作简便，患者痛苦小，费用低，能明显提高患者的生活质量，延长存活时间，是一种值得研究的治疗方法。
Objective: To evaluate the curative effect of hypertonic peritoneal dialysis and simple peritoneal dialysis enema on patients with chronic renal failure (CRF) uremia. Methods: Sixty-one patients were randomly divided into two groups. The treatment group with Chinese medicine plus 4.25% B5185 high permeability dialysate enema, the control group simply applied 4.25% B5185 high permeability dialysis enema, each 300ml, 2 times a day, each time for more than 2 hours. Results: The total effective rate was 88.57% in the treatment group and 80.77% in the control group. There was no significant difference between the two groups (P> 0.05). After treatment, the blood urea nitrogen, creatinine and creatinine clearance rate were significantly improved (P all <0.05). CONCLUSION: Chinese medicine plus peritoneal dialysis enema or simple transdermal peritoneal enema, are effective drugs for the treatment of CRF uremia. This method is easy to operate, patient suffering is small, the cost is low, can significantly improve the quality of life of patients, prolonging survival time is a worthy of study treatment.