论文部分内容阅读
本文对不同年龄组健康人血清免疫球蛋白(Ig)、循环免疫复合物(CIC)和游离自身抗体(auto-Ab)的含量进行同步测定。结果发现,血清IgG含量随增龄无明显改变,老年组IgA明显高于青壮年组和老年前期组,而IgM从45岁便开始下降,老年人降低更为显著;老年组血清IgG含量与CIC-IgG、auto-Ab-IgG含量呈明显正相关;CIC-IgG/血清IgG明显高于其他年龄组,提示其体内有免疫复合物滞留。这说明,评价老年人体液免疫功能时,不仅要测定血清Ig含量,而且要测定CIC-Ig和auto-Ab-Ig的含量。
In this paper, the levels of serum immunoglobulin, circulating immune complex (CIC) and auto-Ab in healthy people of different age groups were measured synchronously. The results showed that the serum IgG content with age did not change significantly in the elderly group IgA was significantly higher than the young group and the elderly group, and IgM began to decline from 45 years old, the elderly decreased more significantly; elderly serum IgG levels and CIC -IgG, auto-Ab-IgG content was significantly positive; CIC-IgG / serum IgG was significantly higher than other age groups, suggesting that the immune complex in vivo retention. This shows that the evaluation of the elderly humoral immune function, not only to determine the serum Ig content, but also to determine the content of CIC-Ig and auto-Ab-Ig.