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目的:观察微生态制剂联合母乳喂养治疗极低出生体重儿喂养不耐受的临床疗效。方法:回顾性总结该院2010年6月~2013年6月新生儿重症监护病房收治的喂养不耐受早产儿(均为极低出生体重儿)68例,并根据是否加用微生态制剂和给予母乳喂养,随机将患儿分为两组,对照组34例,治疗组34例。两组均给予常规治疗:如治疗原发病,静脉营养支持,微量喂养支持等。对照组在常规治疗基础上加用早产儿配方奶喂养,治疗组在常规治疗基础上加用微生态制剂和母乳喂养。比较两组患儿的临床情况,并进行分析。结果:治疗组患儿腹胀及呕吐消失时间、胃潴留消失时间、恢复至出生体重时间及达全肠内营养时间均较对照组缩短,两组差异有统计学意义(P<0.05)。结论:微生态制剂联合母乳喂养治疗极低出生体重儿喂养不耐受安全有效,经济实惠,值得临床推广。
Objective: To observe the clinical effect of probiotics combined with breastfeeding on feeding intolerance in very low birth weight infants. Methods: A retrospective review of 68 patients with intolerant preterm infants (both of whom had very low birth weight) admitted to the Neonatal Intensive Care Unit from June 2010 to June 2013 in the hospital was conducted. According to whether or not to add the probiotics and Give breastfeeding, randomly divided the children into two groups, the control group of 34 patients, the treatment group of 34 patients. Both groups were given conventional treatment: such as the treatment of primary disease, intravenous nutritional support, trace support and so on. Control group on the basis of conventional treatment plus preterm infant formula feeding, the treatment group on the basis of conventional treatment with probiotics and breastfeeding. The clinical situation of the two groups was compared and analyzed. Results: The disappearance of abdominal distension and vomiting, disappearance of gastric retention, recovery to birth weight and total enteral nutrition time in the treatment group were shorter than those in the control group. There was significant difference between the two groups (P <0.05). Conclusion: The combination of probiotics and breastfeeding in the treatment of very low birth weight infants with infertility is safe, effective, economical and worthy of clinical promotion.