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经胃灌入后,~(59)Fe在大鼠内的整体滞留,能很好地拟合二项指数方程。幼年组与成年组的慢组分生物半排期,分别为95d及109d,无统计学显著性差别。~(59)Fe的主要分布器官是肝与骨髓。~(59)Fe在器官中的滞留方程为一项或二项指数式。在幼年组多数器官中,~(59)Fe排出比成年组快。幼年组的剂量特点是多数器官总累积剂量较大,剂量累积速度较快。口服同量的~(59)Fe,对幼年鼠有较大生物效应。
After gastric instillation, the retention of ~ (59) Fe in rats can well fit the binomial exponential equation. Slow biological half-life of young and adult groups was 95d and 109d, respectively, with no significant difference. ~ (59) The main distribution of Fe is liver and bone marrow. ~ (59) Fe in the organism retention equation is one or two exponential. In most organs of juvenile group, ~ (59) Fe excreted faster than the adult group. The dose characteristics of juvenile group is that the cumulative dose of most organs is larger and the dose is accumulated faster. Oral administration of the same amount of ~ (59) Fe has a large biological effect on young rats.