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目的了解慢性苯中毒临床特点及治疗转归情况。方法回顾性对比分析湖南省职业病防治院自1970—2010年随诊的18例慢性苯中毒患者临床症状及治疗转归情况。结果 94.4%的患者存在头晕、乏力慢性苯中毒等非特异性临床表现,50.5%的患者存在出血征象,44.4%的患者有睡眠不佳表现。经早期脱离苯作业及临床治疗,头晕、乏力等临床表现明显减轻,66.7%苯中毒患者病情好转,43.75%轻、中度苯中毒患者痊愈。结论慢性苯中毒患者临床表现以头晕、乏力等非特异性症状为主,疾病预后较好,尤其是轻、中度中毒预后更好。
Objective To understand the clinical features of chronic benzene poisoning and treatment outcome. Methods The clinical symptoms and treatment outcome of 18 patients with chronic benzene poisoning who were followed up from 1970 to 2010 in Hunan Occupational Disease Prevention and Control Hospital were retrospectively analyzed. Results 94.4% patients had nonspecific clinical manifestations of dizziness, fatigue and chronic benzene poisoning, 50.5% had bleeding signs, and 44.4% had poor sleep performance. The clinical manifestations of dizziness, fatigue and other symptoms were significantly relieved after the early release of benzene and clinical treatment, 66.7% benzene poisoning patients improved, 43.75% of light and moderate benzene poisoning patients recovered. Conclusion The clinical manifestations of patients with chronic benzene poisoning are dizziness, fatigue and other non-specific symptoms, the prognosis of the disease is better, especially mild to moderate poisoning prognosis.