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[目的]探讨食管癌颈部吻合术后喉返神经损伤的原因及其防治措施。[方法]对2005～2010年415例行食管癌颈部吻合术的患者资料进行回顾性分析,其中术后并发喉返神经损伤24例。[结果]24例喉返神经损伤包括22例单侧损伤和2例双侧损伤。喉返神经损伤与肿瘤T分期和TNM分期无关。颈段、胸上段食管癌患者较胸中段及下段食管癌患者易发生损伤(P<0.05);上纵隔淋巴结转移的食管癌患者较无淋巴结转移患者更易发生损伤(P<0.05)。[结论]喉返神经损伤与肿瘤位置及上纵隔淋巴结转移相关。
[Objective] To investigate the causes of recurrent laryngeal nerve injury after esophageal cancer anastomosis and its prevention and treatment. [Methods] The data of 415 patients with cervical esophageal anastomosis from 2005 to 2010 were retrospectively analyzed. There were 24 cases of recurrent laryngeal nerve injury after operation. [Results] Twenty-four cases of recurrent laryngeal nerve injury included 22 cases of unilateral injury and 2 cases of bilateral injuries. Recurrent laryngeal nerve injury has nothing to do with tumor T stage and TNM stage. The cervical and thoracic esophageal cancer patients were more likely to be damaged than those in the middle and lower esophageal cancer patients (P <0.05). The patients with esophageal cancer with lymph node metastasis were more likely to be injured than those without lymph node metastasis (P <0.05). [Conclusion] The injury of recurrent laryngeal nerve is related to tumor location and lymph node metastasis of the mediastinum.