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单纯型肾病是一种病因和发病机理尚末明确的肾小球疾病。由于在本病肾脏活体组织检查中没有免疫复合物和补体的沉积,也未发现明显的单核细胞浸润,所以免疫损伤的机理未能得到证实。尽管如此,但仍有不少资料表明单纯型肾病在体液免疫和细胞免疫方面都有程度不同的改变。我科从1979年以来较系统地观察了30例单纯型肾病患儿体液免疫和细胞免疫的变化,并发现一部分乙型血清肝炎表面抗原阳性的病例。现将结果报告如下。
Simple nephropathy is a cause and pathogenesis of yet clear glomerular disease. Because of the absence of deposition of immune complexes and complement in the renal biopsy of this disease and no significant mononuclear cell infiltrates, the mechanism of immune damage has not been demonstrated. In spite of this, there is still a lot of data showing that nephrosis of the simplex has varying degrees of change in both humoral and cellular immunity. Since 1979, our department has systematically observed the changes of humoral and cellular immunity in 30 cases of simple nephrotic syndrome and found that some cases of HBsAg positive cases. The results reported below.