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目的:探讨大黄防治多器官功能不全综合征(MODS)的临床疗效。方法:对收治ICU的615例危重病人,治疗组260例,在常规治疗的基础上给予大黄鼻饲(20g/d),分3～4次;对照组355例,只给予常规(不用大黄)治疗。两组病人的病情及其他治疗方法无差异。统计观察两组病人MODS的发生率及病死率。结果:615例危重病人发生MODS98例。MODS的发生率治疗组11.15%,对照组19.44%。发生MODS的患者死亡64例。MODS病死率治疗组为48.28%,对照组为72.46%。两组病人MODS的发生率和病死比较具有统计学意义。结论:大黄治疗危重病患者可降低MODS的发生率,提高MODS的抢救成功率。
Objective: To investigate the clinical efficacy of rhubarb in the prevention and treatment of multiple organ dysfunction syndrome (MODS). Methods: A total of 615 critically ill patients admitted to the ICU were enrolled in this study. 260 patients in the treatment group were given Rhubarb nasal feeding (20g / d) on a routine basis for 3 to 4 times. In the control group, 355 patients were given routine (without rhubarb) . There was no difference between the two groups of patients and other treatment methods. The incidence of MODS and mortality in two groups were observed. Results: There were 98 cases of MODS in 615 critically ill patients. The incidence of MODS was 11.15% in the treatment group and 19.44% in the control group. Sixty-four patients died of MODS. MODS mortality rate was 48.28% in the treatment group and 72.46% in the control group. Two groups of patients with MODS incidence and mortality compared with statistically significant. Conclusion: Rhubarb treatment of critically ill patients can reduce the incidence of MODS and improve the success rate of rescue MODS.