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目的探讨美沙拉嗪治疗溃疡性结肠炎的临床效果。方法选取我院消化内科住院的溃疡性结肠炎患者62例,随机将其分为两组,观察组患者采用美沙拉嗪治疗,对照组患者采用柳氮磺吡啶进行治疗,对两组患者的治疗效果进行比较。结果观察组和对照组患者的总有效率分别为93.5%、77.4%,观察组治疗效果优于对照组,差异有统计学意义(P<0.05);观察组患者不良反应发生率为9.7%,对照组患者不良反应发生率为32.3%,差异有统计学意义(P<0.05)。结论美沙拉嗪治疗溃疡性结肠炎不良反应少,且安全有效。
Objective To investigate the clinical efficacy of mesalazine in the treatment of ulcerative colitis. Methods 62 patients with ulcerative colitis hospitalized in our hospital were randomly divided into two groups. The patients in the observation group were treated with mesalazine and the patients in the control group were treated with sulfasalazine. The treatment of the two groups of patients The effect is compared. Results The total effective rates of the observation group and the control group were 93.5% and 77.4%, respectively. The treatment effect in the observation group was superior to that in the control group (P <0.05). The incidence of adverse reactions in the observation group was 9.7% The incidence of adverse reactions in the control group was 32.3%, the difference was statistically significant (P <0.05). Conclusion Mesalazine treatment of ulcerative colitis with less adverse reactions, and safe and effective.