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作者报道了一例严重的原发性血小板减少性紫癜(ITP),并发眶下神经感觉异常和口腔粘膜出血性大疱的病例。一位菲律宾籍的36岁妇女,一周前有全身不适和乏力史,之后在其舌的左、右侧缘,左下牙槽粘膜和下唇出现直径1cm的血疱,以及右眶下神经区域青紫和感觉异常。全身体检时发现躯干和四肢有泛发性的紫癜。心血管和呼吸系统正常,无肝脾肿大,中枢和周围神经系统正常。血小板计数仅有6×10~9/L。骨髓穿刺发现骨髓巨核细胞增多。血清学检查排除了其它原因引起的血小板减少性紫癜,诊断为ITP。
The authors reported a case of severe idiopathic thrombocytopenic purpura (ITP) complicated by infraorbital nerve sensory abnormalities and oral mucosal hemorrhagic bullous bursa. A Filipino 36-year-old woman, who had generalized malaise and weakness one week earlier, developed blood blisters of 1 cm in diameter at the left and right side margins of the tongue, the left lower alveolar mucosa and the lower lip, and bruising in the right infraorbital nerve region And feeling abnormal. Physical examination found that trunk and limbs with purpura. Cardiovascular and respiratory system is normal, no hepatosplenomegaly, central and peripheral nervous system normal. Platelet count only 6 × 10 ~ 9 / L. Bone marrow punctate bone marrow megakaryocytes increased. Serological tests excluded other causes of thrombocytopenic purpura, the diagnosis of ITP.