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峨嵋茶为四川峨嵋山生长的一种优质绿茶。本文采用小鼠微核试验、小鼠精子畸变试验、姊妹染色单体互换试验对峨嵋茶及其茶多酚的抗突变作用进行研究。结果：峨嵋菜水浸液浓度为１．２５％—２．５％时，对环磷酰胺诱发小鼠骨髓嗜多染红细胞微核抑制率为４１％—４５％、小鼠精子畸变抑制率为７３．５％—８２．３％、每毫升培养液含峨嵋菜水浸液２０、２００ｍｇ、峨嵋茶茶多酚２、２０、２００ｍｇ时，对丝裂霉素Ｃ诱发人外周血淋巴细胞姊妹染色单体互换抑制率分别为３７．５％—４９．５９％；３６．１２％—６９．８１％。表明：峨嵋茶及其茶多酚对环磷酰胺诱发小鼠骨髓微核出现率、小鼠精子畸变率、丝裂霉素Ｃ诱发人外周血淋巴细胞姊妹染色单体互换率均有较好抑制作用。
Tea is a kind of high-quality green tea grown in Lushan, Sichuan Province. In this paper, mouse micronucleus test, mouse sperm aberration test, and sister chromatid exchange test were used to study the antimutagenicity of wolfberry tea and its tea polyphenols. RESULTS: When the aqueous extract concentration of leeks was 1.25%—2.5%, the micronucleus inhibition rate of polychromatic erythrocytes in bone marrow induced by cyclophosphamide was 41%—45%, and the inhibition rate of sperm distortion in mice was When 73.5%-82.3% of the culture solution containing 20,200mg leek extract, 2,20, 200mg tea polyphenols, the sister chromatogram of human peripheral blood lymphocytes induced by mitomycin C The body exchange inhibition rates were 37.5% to 49.59% and 36.12% to 69.81%, respectively. The results showed that tea and its polyphenols had better effects on the occurrence of micronucleus in mice bone marrow induced by cyclophosphamide, the rate of mouse sperm aberration, and sister chromatid exchange rate induced by mitomycin C in peripheral blood lymphocytes. Inhibition.