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抗雄激素是一种能抑制雄激素对其靶细胞起作用的化合物.此类化合物在治疗因雄激素所致之皮肤病中有潜在的重要性.在西德,内用抗雄激素治疗女性的皮脂溢出病、寻常性痤疮、多毛症及男性型秃发已有数年,看来今后用它治疗患此类皮肤病的女病人会有所增多.本文复习抗雄激素的作用方式及其在皮肤科的应用.雄激素对靶细胞的刺激作用性腺及肾上腺产生各种雄激素,它们的生物化学内在关系颇为复杂.在血循中,最重要的雄激素是睾酮,在5α还原酶的影响
Anti-androgens are compounds that inhibit the effects of androgens on their target cells and are of potential importance in the treatment of androgen-induced dermatoses.In western Germany, anti-androgens were used in women Of seborrhea, acne vulgaris, hirsutism and male alopecia have been for years, it appears that the future use it to treat women suffering from such skin diseases will be increased.This article review the anti-androgen action mode and its Dermatology and the role of androgen stimulation of the target cells The gonad and the adrenal glands produce a variety of androgens, their biochemical relationships are quite complicated.In the bloodstream, the most important androgen is testosterone, 5α reductase influences