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梅克尔软骨来源于第一鳃弓,在下颌骨的生长发育、锤骨和砧骨的形成中起重要作用。作为下颌骨早期发育的支架,梅克尔软骨在出生之后逐渐消亡。本文就梅克尔软骨消亡的分子机制作一综述。
Merkel cartilage originates from the first branchial arch and plays an important role in the growth and development of the mandible and in the formation of the malleus and incus. As a scaffold for the early development of the mandible, Merkel cartilage gradually fades after birth. This article reviews the molecular mechanisms of merkel cartilage disappearance.