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为确定医院内医原性因素对产生肾机能不全的作用,作者研究了2,262例的内外科住院患者,发现医院内获得性肾机能不全(HARI)引起的死亡率仍然很高。 2,262名患者是1978年9月至1979年2月间住进Tufts新英格兰医疗中心普通内外科的,他们因肾机能不全的发生和日益恶化而在整个住院期间受到预期性的研究。作者规定的肾机能不全为:(1)血清肌酐基线水平≤1.9mg/dl(168μmol/l)的患者其血清肌酐增加≥0.5mg/dl(44.2μmol/l);(2)血清肌酐基线水
To determine the role of hospital-based iatrogenic factors in the development of renal insufficiency, the authors studied 2,262 inpatient surgical patients and found that there was still high mortality from hospital-acquired renal insufficiency (HARI). 2,262 patients were admitted to the General Surgery Department of Tufts New England Medical Center from September 1978 to February 1979 and were expected to study throughout the hospital because of the occurrence and worsening of renal insufficiency. The renal insufficiency prescribed by the authors was: (1) a serum creatinine increase of 0.5 mg / dL (44.2 μmol / l) was observed in patients with serum creatinine baseline levels ≤1.9 mg / dl (168 μmol / l); (2) baseline serum creatinine