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目的探讨布地奈德混悬液联合特布他林雾化液吸入治疗咳嗽变异性哮喘的临床疗效。方法将82例咳嗽变异性哮喘患儿随机分成治疗组42例与对照组40例,对照组给予布地奈德混悬液雾化吸入治疗,其中6岁以下0.5mg/次,6岁以上1mg/次,每日2次。治疗组在对照组的基础上再给予特布他林雾化液联合吸入治疗,体重20kg以下2.5mg/次,20kg以上5mg/次,每日2次。观察两组的疗效及不良反应。结果总有效率:治疗组95.24%,对照组的75.00%,两组比较差异有统计学意义(χ2=6.72,P<0.01)。显效率:治疗组83.33%,对照组的60.00%,两组比较差异有统计学意义(χ2=5.53,P<0.05)。结论布地奈德混悬液联合特布他林雾化液吸入治疗咳嗽变异性哮喘疗效满意。
Objective To investigate the clinical efficacy of budesonide suspension combined with terbutaline as nebulizer in the treatment of cough variant asthma. Methods Eighty-two children with cough variant asthma were randomly divided into treatment group (n = 42) and control group (n = 40). The control group was treated with budesonide suspension inhalation therapy, 0.5mg / Times, 2 times a day. The treatment group was given Terbutaline nebulization combined with inhalation therapy on the basis of the control group, body weight below 20kg 2.5mg / time, 20kg above 5mg / time, 2 times a day. The curative effect and adverse reaction of the two groups were observed. Results The total effective rate was 95.24% in the treatment group and 75.00% in the control group, with significant difference between the two groups (χ2 = 6.72, P <0.01). The markedly effective rate was 83.33% in the treatment group and 60.00% in the control group, with significant difference between the two groups (χ2 = 5.53, P <0.05). Conclusions Budesonide suspension combined with terbutaline inhalation is effective in treating cough variant asthma.