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目的观察甲磺酸罗哌卡因复合舒芬太尼硬膜外阻滞用于分娩镇痛的效果和安全性。方法选取2009年1月～2010年10月的收治的主动要求行分娩镇痛、健康、单胎、足月临产初产妇200例,随机分为两组,各100例。镇痛组分娩前给予低浓度甲磺酸罗哌卡因加芬太尼,宫口开全后停止注药。对照组不行无痛分娩。观察两组临床效果。结果分娩镇痛对产程无明显影响,产妇无恶心、呕吐、皮肤瘙痒、尿潴留等不良反应。对照组产妇的血压、心率、呼吸频率明显比镇痛组高(P<0.05)。结论甲磺酸罗哌卡因配伍舒芬太尼用于分娩镇痛的临床效果显著,对母婴无不良影响,安全有效,值得临床推广应用。
Objective To observe the efficacy and safety of ropivacaine mesylate combined with sufentanil epidural block for labor analgesia. Methods From January 2009 to October 2010 admitted to take the initiative to request delivery analgesia, health, single birth, term full-term primipara 200 cases were randomly divided into two groups of 100 cases. Analgesic component given low concentrations of ropivacaine mesylate plus fentanyl before delivery, cervix to stop injection. Control group no painless childbirth. The clinical effects of two groups were observed. Results labor analgesia had no significant effect on labor, maternal nausea, vomiting, pruritus, urinary retention and other adverse reactions. The blood pressure, heart rate and respiratory rate in the control group were significantly higher than those in the analgesic group (P <0.05). Conclusion The clinical effect of ropivacaine mesylate and sufentanil used for labor analgesia is significant, it has no adverse effect on maternal and infant, safe and effective, and worthy of clinical application.