本文对68例胎膜早破(PROM)者,监测 C-反应性蛋白(CRP)和体温、白细胞计数分类、IgM、胎盘胎膜病理学检查,发现并发羊膜炎52例(76%),正常羊膜16例(24%).CRP 和传统方法比较,发现 CRP 敏感性、特异性最高,分别为98%和87.5%,且破膜时间越长 CRP 值越高,胎盘胎膜炎症越重,治疗后 CRP 下降者胎儿预后好,反之差. In this paper, 68 cases of premature rupture of membranes (PROM), monitoring of C-reactive protein (CRP) and body temperature, white blood cell count classification, IgM, placental fetal pathology and found that amniocentesis in 52 cases (76% 16 cases of amniotic membrane (24%) .Compared with traditional methods, CRP showed the highest sensitivity and specificity of CRP, which were 98% and 87.5% respectively. The longer the time of rupture was, the higher of CRP was. Post-CRP decline in fetus good prognosis, on the contrary.