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目的探讨新疆地区维吾尔族人群泌尿系结石与电解质及血脂的相关性。方法回顾性分析2013年3~12月于新疆医科大学第二附属医院就诊的138例维吾尔族泌尿系结石患者(病例组)和94例同期在笔者医院健康体检正常者(对照组),健康体检时及患者入院后采集的外周血样本资料,检测电解质观察指标血钙、磷、钠、镁;血脂观察指标甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)水平,比较两组各观察指标水平有无差异,并采用SPSS 17.0软件对其进行t检验。结果两组受检者血钙、血磷、血镁水平比较,差异均有统计学意义(P<0.05),而两组血钠水平差异无统计学意义(P>0.05);两组受检者血清TG、HDL-C、LDL-C水平比较,差异均有统计学意义(P<0.05);而两组血清TC水平比较,差异无统计学意义(P>0.05)。结论血钙、血磷、血镁水平以及TG、HDL-C、LDL-C水平可能是影响泌尿系结石形成的危险因素之一。
Objective To investigate the correlation between urinary calculi and electrolytes and blood lipids in Uygur population in Xinjiang Uygur Autonomous Region. Methods A retrospective analysis of 138 Uighur urolithiasis cases (case group) and 94 cases of normal Uygur patients (control group) hospitalized at the Second Affiliated Hospital of Xinjiang Medical University from March 2013 to December 2013 was performed. The physical examination (P <0.05), and the data of peripheral blood samples collected after the patients were admitted to the hospital to detect the electrolyte calcium, phosphorus, sodium and magnesium; the indexes of blood lipid triglyceride (TG), total cholesterol (TC), high density lipoprotein (HDL- , Low density lipoprotein (LDL-C) levels were compared between the two groups were no differences in the level of indicators, and using SPSS 17.0 software t test. Results There were significant differences in serum calcium, serum phosphorus and magnesium between the two groups (P <0.05), but there was no significant difference in serum sodium between the two groups (P> 0.05) The levels of serum TG, HDL-C and LDL-C were significantly different between the two groups (P <0.05). There was no significant difference in serum TC levels between the two groups (P> 0.05). Conclusion The levels of serum calcium, phosphorus, magnesium and levels of TG, HDL-C and LDL-C may be one of the risk factors of urolithiasis.