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肌红蛋白尿症多见于肌肉外伤、癫痫、药物过量及剧烈运动等。以往认为病毒引起者较少。近年来报道柯萨奇A_9、疱疹病毒及香港甲型流感病毒可和有/或无肾功能衰竭的肌红蛋白尿有关。其发病机理不甚清楚,可能为病毒的免疫复合物的损害或弥漫性血管内凝血之结果。本文报道3例流感引起的肌红蛋白尿性肾功能衰竭。作者所在的医学中心,2年内收治7例肌红蛋白尿性肾功能衰竭病人,流感引起者占首位。其他4例为酒精性肌病、急进性多发性肌炎及大血管外科手术后并发症。
Myoglobinuria more common in muscle trauma, epilepsy, overdose and strenuous exercise and so on. In the past that the virus caused less. In recent years, it has been reported that coxsackie A_9, herpes virus and influenza A virus of Hong Kong may be associated with myoglobinuria with / without renal failure. Its pathogenesis is unclear and may be the result of damage to the immune complex of the virus or disseminated intravascular coagulation. This article reports 3 cases of influenza caused by myoglobinuria renal failure. The author’s medical center, admitted within 2 years 7 cases of myoglobinuria renal failure patients, flu caused by the first person. The other 4 cases were alcoholic myopathy, acute polymyositis and complications after macrovascular surgery.