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目的:了解2016-2020年天津市性传播疾病(STD)门诊男性就诊者HIV感染状况及其相关因素。方法:采用横断面调查方法,2016-2020年的每年4-6月,每个哨点样本量为400人,连续监测并收集天津市STD门诊男性就诊者的艾滋病知识知晓率、相关性行为,以及HIV、梅毒、HCV感染等信息。结果:STD门诊男性就诊者共4 000例。2016-2020年HIV阳性率由1.13%(9/800)增长到2.25%(18/800)(趋势n χ2=14.22,n P<0.001),梅毒阳性率由9.38%(75/800)增长到13.00%(104/800)(趋势n χ2=7.30,n P=0.007),总HCV阳性率为0.45%(18/4 000)。多因素logistic回归分析结果显示,分别相比于未婚、天津市户籍、最近3个月未发生临时性行为、未发生同性肛交和未感染梅毒者,STD门诊男性就诊者感染HIV危险因素包括同居(an OR=7.53,95%n CI:2.13~26.62)、外省户籍(an OR=3.64,95%n CI:1.58~8.38)、最近3个月发生临时性行为(an OR=2.24,95%n CI:1.03~4.89)、发生同性肛交(an OR=85.99,95%n CI:38.76~190.74)和感染梅毒(an OR=6.06,95%n CI:3.18~11.56)。n 结论:2016-2020年天津市STD门诊男性就诊者的HIV和梅毒阳性率呈上升趋势,发生临时性行为、同性肛交和感染梅毒是STD门诊男性就诊者HIV感染的主要危险因素。“,”Objective:To understand the HIV infection status in male outpatients in sexually transmitted disease (STD) clinics in Tianjin from 2016 to 2020.Methods:According to the sentinel surveillance protocol, continuous cross-sectional studies were conducted between April and June during 2016-2020 to collect the information about the awareness of AIDS related knowledge, related sex behaviors, HIV infection, syphilis prevalence and HCV infection of male STD outpatients in Tianjin with a sample seize of 400 in each sentinel clinic.Results:From 2016 to 2020, a total of 4 000 male STD outpatients were surveyed. The HIV positive rate increased from 1.13% (9/800) to 2.25% (18/800) (trend n χ2=14.22,n P<0.001), the positive rate of syphilis increased from 9.38% (75/800) to 13.00% (104/800) (trendn χ2=7.30, n P=0.007) in this population during this period. The overall HCV positive rate was 0.45% (18/4 000). Multivariate logistic regression analysis showed that compared with those who were unmarried, had registered residence in Tianjin, had no temporary sexual behavior in the past 3 months, had no anal sex and had negative syphilis test result, the risk factors of HIV infection in the male STD outpatients included cohabitation (an OR=7.53, 95%n CI:2.13-26.62), being from other provinces (an OR=3.64,95%n CI:1.58-8.38), having temporary sexual behavior in the past 3 months (an OR=2.24,95%n CI:1.03-4.89), having homosexual anal sex (an OR=85.99,95%n CI:38.76-190.74) and suffering from syphilis (an OR=6.06,95%n CI:3.18-11.56).n Conclusion:The detection rates of HIV infection and syphilis in male STD outpatients in Tianjin showed upward trends from 2016 to 2020. Having temporary sexual behavior and anal sex, and suffering from syphilis were the main risk factors of HIV infection in male STD outpatients.