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目的观察小剂量地西泮联合奥美拉唑、克拉霉素、甲硝唑治疗舰艇部队人员消化性溃疡的临床效果。方法将60例消化性溃疡患者随机分为治疗组和对照组各30例。对照组采用奥美拉唑、克拉霉素、甲硝唑治疗,治疗组在对照组基础上加用小剂量地西泮治疗。对比2组临床疗效、HP转阴率及0.5年复发率。结果治疗后,治疗组总有效率、HP转阴率均高于对照组,0.5年复发率低于对照组,差异均有统计学意义(P<0.05)。结论小剂量地西泮联合奥美拉唑、克拉霉素、甲硝唑治疗舰艇部队人员消化性溃疡治愈率高,复发率低,值得推广应用。
Objective To observe the clinical efficacy of low-dose diazepam combined with omeprazole, clarithromycin and metronidazole in the treatment of peptic ulcer in naval vessels. Methods Sixty patients with peptic ulcer were randomly divided into treatment group and control group with 30 cases each. The control group was treated with omeprazole, clarithromycin and metronidazole. The treatment group was treated with low-dose diazepam on the basis of the control group. The clinical efficacy, the negative conversion rate of HP and the recurrence rate of 0.5 year were compared between the two groups. Results After treatment, the total effective rate and the negative conversion rate of HP in the treatment group were higher than those in the control group, and the recurrence rates at 0.5 year were lower than those in the control group (P <0.05). Conclusion Low-dose diazepam combined with omeprazole, clarithromycin and metronidazole in the treatment of peptic ulcer in naval vessel units has high cure rate and low recurrence rate, which deserved to be popularized and applied.