论文部分内容阅读
本文旨在探讨阻塞性肺疾病患者吸入大剂量二丙酸氯地米松(BDP)的疗效,是否与口服皮质醇的疗效相同。22例(男16,女6,年龄39～84岁)门诊病人,患有中至重度气道阻塞,FEV_1 1.31(0.5～2.4)L,FVC2.3(0.6～4.1)L,最大呼气流量(PEFR)255(60～350)L/min。全部病人以单盲法连续进行6周实验,每2周为1单元:①吸入安慰剂和口服安慰片(1,2周);②口服安慰片并吸入BDP500ug bid(3,4周);③强地松片30mg/d(5,9周)。上述肺通气
This article aims to investigate the efficacy of high-dose inhaled beclomethasone dipropionate (BDP) in patients with obstructive pulmonary disease, whether or not the same effect as oral cortisol. Twenty-two outpatients (16 males, 6 females, aged 39-84 years) with moderate to severe airway obstruction, FEV_1 1.31 (0.5-2.4) L, FVC 2.3 (0.6-4.1) L and maximum expiratory flow (PEFR) 255 (60 to 350) L / min. All patients were given a single blinded continuous 6-week experiment with 1 unit every 2 weeks: Placebo and placebo tablets (1,2 weeks); Oral comfort tablets and inhaled BDP 500ug bid (3,4 weeks); Strong pine tablets 30mg / d (5,9 weeks). The above lung ventilation