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目的：分析子宫内膜复杂性增生过长伴非典型性临床病理特点。方法：对２４例子宫内膜复杂性增生过长伴非典型性子宫内膜进行光镜观察及免疫组化染色。结果：２４例中，４例发展为子宫内膜腺癌，７例痊愈，１０例好转，３例在随访中。内膜癌患者的ＰＣＮＡ检测均为阳性高表达。结论：子宫内膜复杂性增生过长伴非典型性，其病变的发展是双向的，即可癌变，也可逆转。预后评估取决于患者的年龄及免疫组化检测的结果
Objective: To analyze the clinicopathological features of atypical hyperplasia complicated with endometrial hyperplasia. Methods: 24 cases of endometrial hyperplasia complicated with atypical endometrium were observed by light microscopy and immunohistochemistry. Results: Of the 24 cases, 4 developed endometrial adenocarcinoma, 7 recovered, 10 improved and 3 were followed up. PCNA in patients with endometrial cancer were positive for high expression. Conclusion: The complicated endometrial hyperplasia with atypia, the development of the disease is two-way, can be cancer, but also reversible. Prognosis assessment depends on the patient’s age and immunohistochemistry results