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以往的实验表明 ,乙型肝炎病毒 (hepatitisBvirus,HBV)的preS1-(2 1-4 7)序列直接参与病毒与细胞膜受体的粘附 ;HepG2细胞膜上存在HBV受体活性的蛋白质。本文作者利用人工合成的 4 preS1 (2 1 47)序列 ,通过亲合色谱法从去垢剂溶解的HepG
Previous experiments showed that the preS1- (2 1-4 7) sequence of hepatitis B virus (HBV) is directly involved in the adhesion of the virus to the cell membrane receptor; and the HBV receptor activity protein exists in the HepG2 cell membrane. Using the synthetic 4 preS1 (2147) sequence, the authors used affinity chromatography to remove HepG from detergent