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目的探究荧光素钠眼底血管造影(FFA)检查确定视网膜中央静脉阻塞(CRVO)分型,并确定有效治疗方法 ,评价FFA在CRVO诊治中的临床应用价值。方法 100例(100眼)CRVO患者作为研究对象,患者100眼进行FFA检查,对检察结果进行前瞻性研究。结果 100眼中早期CRVO动脉血管正常18眼(18%)。中期CRVO阻塞侧动脉血管出现异常主要表现为粗细不均匀40眼(40%)。晚期CRVO阻塞侧动脉血管出现异常主要表现为粗细不均匀42眼(42%)。100眼早期CRVO静脉血管均有扩张或渗漏现象发生。100例毛细血管发生变化患者中属于缺血型CRVO 22例(22%),患者发病早期眼底毛细血管呈现梯田的形状,无灌注。非缺血型CRVO 78例(78%),具体表现为毛细血管扩张导致荧光素渗漏。100例患者全部出现视盘水肿现象,表面由于毛细血管舒张,导致荧光素渗漏。缺血型CRVO患者中有10例患者重新建立了侧支循环。结论 FFA是视网膜中央静脉阻塞的诊断和鉴别诊断、治疗和预后方面的重要检查手段。
Objective To investigate the fundus fluorescein angiography (FFA) to determine the type of central retinal vein occlusion (CRVO), and to determine the effective treatment methods to evaluate the clinical value of FFA in the diagnosis and treatment of CRVO. Methods One hundred patients (100 eyes) with CRVO were enrolled in this study. One hundred eyes of 100 patients underwent FFA and the prospective study was conducted. Results The early CRVO arteries in 18 eyes (18%) were normal in 100 eyes. Mid-term CRVO obstructive lateral artery abnormalities showed mainly uneven thickness of 40 (40%). Late CRVO obstructive lateral artery abnormalities showed mainly uneven thickness of 42 eyes (42%). 100 eyes of early CRVO venous vessels have expansion or leakage occurred. Totally 22 cases (22%) of 100 cases with changes of capillaries were ischemic CRVO. The early stage of the onset of fundus showed the shape of terraced capillaries with no perfusion. 78 cases of non-ischemic CRVO (78%), manifested as telangiectasia leading to fluorescein leakage. All 100 cases of optic disc edema phenomenon, the surface due to capillary relaxation, leading to fluorescein leakage. Ten patients with ischemic CRVO regained collateral circulation. Conclusion FFA is an important diagnostic method for differential diagnosis, treatment and prognosis of central retinal vein occlusion.