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目的了解亳州市农村居民戊型肝炎病毒感染状况,为制定戊肝防控策略和措施提供依据。方法采用多阶段抽样法在4县区各随机抽取1个乡镇的1个行政村共计1 595名居民,采用酶联免疫吸附试验检测戊肝病毒IgG抗体,进行血清学调查分析。结果 1 595名居民戊肝病毒IgG抗体阳性率为14.98%,其中男性为12.35%(90/729),女性为17.21%(149/866),阳性率差异有显著性(χ2=7.34,P<0.05);对地区、文化程度、职业、年龄组抗体阳性率分组比较显示,各组间差异均有显著性意义,随年龄增长抗体阳性率呈上升趋势。结论亳州市农村居民中戊型肝炎病毒感染率与性别、居住地区、年龄、职业以及文化程度有关,亳州市农村居民戊肝防控现状不容忽视,应加强戊肝的监测和防控。
Objective To understand the status of hepatitis E virus infection among rural residents in Bozhou and provide evidence for the development of prevention and control strategies and measures for hepatitis E. Methods A total of 1 595 residents were randomly selected from 1 administrative village of 1 township in 4 counties and districts by multi-stage sampling method. The hepatitis E virus IgG antibodies were detected by enzyme linked immunosorbent assay and serological investigation. Results The positive rate of hepatitis E virus IgG antibody in 1 595 residents was 14.98%, of which 12.35% (90/729) in male and 17.21% (149/866) in female, the difference was significant (χ2 = 7.34, P < 0.05). The comparison of antibody positive rate among different regions, education level, occupation and age group showed that there was significant difference among all groups. The positive rate of antibody increased with age. Conclusion The prevalence of hepatitis E virus among rural residents in Bozhou is related to sex, living area, age, occupation and educational level. The status of prevention and control of hepatitis E in rural residents in Bozhou can not be ignored. Monitoring and prevention and control of hepatitis E should be strengthened.