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目的:通过开展中西医结合综合治疗方案治疗小儿支原体肺炎的临床疗效评价研究,评价中医药在小儿支原体肺炎治疗中的有效性和安全性。方法:本临床试验为多中心、前瞻性队列研究,按照治疗方案的不同,自然形成单纯西医治疗组(西医组)和中西医结合治疗组(中西医组)。西医组采用阿奇霉素基础治疗,中西医组在基础治疗的同时,结合中医内服外治方案。结果:临床疗效西医组的痊愈率为18.9%,显效率为78.9%,有效率为100%(n=90),中西医组痊愈率31.9%,显效率76.8%,有效率为100%(n=310);2组痊愈率比较,差异有统计学意义(P<0.05);2组显效率和有效率比较差异无统计学意义(P>0.05)。结论:中西医组疗效明显优于西医组。
OBJECTIVE: To evaluate the clinical efficacy of traditional Chinese medicine (TCM) in treating children with mycoplasma pneumonia by comprehensive treatment of traditional Chinese medicine and western medicine. To evaluate the effectiveness and safety of Chinese medicine in the treatment of children with mycoplasma pneumonia. Methods: The clinical trial was a multicenter, prospective cohort study. According to the different treatment options, Western medicine group and Western medicine group were formed naturally. Western medicine group with azithromycin basic treatment, Western medicine group in the basic treatment at the same time, combined with Chinese medicine oral administration outside the program. Results: The curative effect of Western medicine group was 18.9%, the effective rate was 78.9%, the effective rate was 100% (n = 90), the cure rate was 31.9%, the effective rate was 100% (n = 310). There was significant difference between the two groups in the cure rate (P <0.05). There was no significant difference in the effective rate and effective rate between the two groups (P> 0.05). Conclusion: The efficacy of traditional Chinese medicine group is better than that of western medicine group.