在人类免疫生物学,特别是T细胞亚群的研究中,细胞表面标志物的表露及这些标志物在细胞亚群功能性状鉴定中发挥的作用已成为极为热门的研究领域。一般认为T细胞具有绵羊红细胞受体(E受体)。这一表面标志物可用于总T细胞群的鉴定。体外T细胞功能测定中已经证明具有T细胞功能的细胞主要是形成E玫瑰花的细胞群,因此这一标志物是很有实用价值的。但是不能认为T细胞就是具有E受体的细胞。虽然我们知道所有具有T细胞功能的细胞都位于E玫瑰花细胞群中,但这并不意味着每一个E玫瑰花细胞必定是T细胞。目前已知某些T细胞结合E的亲合力大大低于 In the study of human immunobiology, especially in T cell subsets, the display of cell surface markers and the role of these markers in the identification of functional traits of cell subsets have become extremely popular research areas. T cells are generally considered to have sheep erythrocyte receptors (E receptors). This surface marker can be used for the identification of total T cell populations. In vitro T-cell function assays have demonstrated that cells with T-cell function are predominantly cell populations that form E-rose, and therefore this marker is of practical value. However, T cells can not be considered as E receptor cells. Although we know that all cells with T cell functions are located in the E rose cluster, this does not mean that every E rose cell must be a T cell. It is known that the affinity of some T cells for binding to E is much lower than that