子宫内膜异位症(EMs)是雌激素依赖性疾病。近年来研究发现,除传统的内分泌机制外,内异症的发生似乎更与异位子宫内膜自分泌机制有关。这表现在异位内膜异常表达芳香化酶,不表达17β-羟甾脱氢酶-2,结果雌激素生成代谢增加,而雌激素分解代谢减少,在局部造成一个高水平的雌激素微环境,是导致内异症病理发生的重要机制。 Endometriosis (EMs) is an estrogen-dependent disease. In recent years, the study found that, in addition to the traditional endocrine mechanisms, the occurrence of endometriosis seems to be more ectopic endometrial autocrine mechanisms. This is manifested in abnormal expression of aromatase in the ectopic endometrium, 17β-hydroxysteroid dehydrogenase-2, which results in increased estrogen production and metabolism, whereas estrogen catabolism is reduced, resulting in a high level of estrogen microenvironment locally , Is an important mechanism leading to the pathogenesis of endometriosis.