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目的 了解柯萨奇B组病毒 (coxackievirusB ,CVB)在病毒性肝炎中的感染情况。方法 用免疫酶法对 2 0 3例各型肝炎组进行CVB 1至 6型免疫球蛋白G(IgG)检测 ,并与 10 5例病毒性心肌炎组及正常对照组进行分析。结果 肝炎组阳性率 (39.9% )高于正常对照组 (13 .4% ) ,P <0 .0 0 5 ,而低于心肌炎组 (5 3 .3% ) ,P <0 .0 2 5 ,B1～ 6型都有一定的检出率 ,且以各型交叉感染为主。结论 病毒性肝炎患者对CVB各型普遍易感 ,其致病性应引起重视与探讨
Objective To understand the infection of coxackievirus B (CVB) in viral hepatitis. Methods CVB type 1 to type 6 immunoglobulin G (IgG) were detected by enzyme immunoassay in 203 hepatitis B patients, and were analyzed with 105 cases of viral myocarditis and normal control group. Results The positive rate of hepatitis group (39.9%) was higher than that of normal control group (13.4%), P <0.05, but lower than that of myocarditis group (53.3%), P < B1 ~ 6 type has a certain detection rate, and to all types of cross-infection-based. Conclusions Patients with viral hepatitis are generally susceptible to various types of CVB and their pathogenicity should be emphasized and discussed