溶血尿毒综合征(HUS)的发病机制仍不明了。肾脏及其它器官(大肠)的血管病变最易解释如下的典型三联征:血性腹泻、微血管病(溶血性贫血和血小板减少)及肾功衰竭。除去某些患者偶显血清补体水平低下及有肾小球免疫球蛋白和补体C_3的沉着物以外,并无其它资料支持免疫机制。有人将本病与特急性同种移植的排斥反应进行比较,研究的结论认为 The pathogenesis of hemolytic uremic syndrome (HUS) remains unclear. Vascular lesions in the kidneys and other organs (the large intestine) most likely explain the typical triad of bloody diarrhea, microangiopathies (hemolytic anemia and thrombocytopenia) and renal failure. In addition to some patients with occasional serum complement levels were low and glomerular immunoglobulin and complement C_3 of the sediment, there is no other information to support the immune mechanism. Some people compared with acute rejection of acute allograft rejection, the study concluded that