己糖激酶Ⅱ基因微卫星多态性与ＮＩＤＤＭ的关系李蕾施珏罗尧生薛元明己糖激酶是葡萄糖代谢途径限速酶，有四种同工酶，Ⅰ、Ⅱ、Ⅲ、Ⅳ型。己糖激酶Ⅱ（ＨＫ２）参与催化骨骼肌葡萄糖磷酸化，且为该途径的限速酶。ＮＩＤＤＭ的一个主要病理生理特点为周围组织尤其是骨骼肌... Relationship between hexokinase Ⅱ gene microsatellite polymorphism and NIDDM LI Lei, SHI Jue, LUO Yao-sheng, XUE Yuan-ming Hexokinase is the rate-limiting enzyme in glucose metabolism. There are four isozymes, Ⅰ, Ⅱ, Ⅲ and Ⅳ. Hexokinase II (HK2) is involved in catalyzing glucose phosphorylation of skeletal muscle and is the rate-limiting enzyme in this pathway. One of the major pathophysiological features of NIDDM is the surrounding tissue, especially skeletal muscle ...