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目的:观察术前糖化血红蛋白(HbAlc)水平对结直肠癌合并糖尿病患者术后恢复的影响。方法:选择结直肠癌合并糖尿病201例,根据术前HbAlc水平分为A组(HbAlc≤7.0%)89例和B组(HbAlc>7.0%)112例。两组麻醉方式和术式相同,比较两组手术时间、术中出血量、术后肛门排气时间、术后住院时间及术后不良反应发生情况等。结果:A组术后住院时间非常显著短于B组(P<0.01),两组手术时间、术中出血量、术后肛门排气时间比较,差异不显著(P>0.05)。A组术后不良反应发生率为13.5%,非常显著低于B组的36.6%(P<0.01)。结论:术前高HbAlc水平的糖尿病合并结直肠癌患者,术后吻合口瘘、心力衰竭、术后感染等不良反应发生率较高,术后住院时间延长。
Objective: To observe the effect of preoperative HbAlc on postoperative recovery of patients with colorectal cancer complicated with diabetes mellitus. Methods: Totally 201 cases of colorectal cancer complicated with diabetes mellitus were selected and divided into group A (HbAlc≤7.0%) 89 cases and group B (HbAlc> 7.0%) 112 cases according to the preoperative HbA1c level. Two groups of anesthesia and surgical procedures the same, the two groups were compared operation time, intraoperative blood loss, postoperative anal exhaust time, postoperative hospital stay and postoperative adverse reactions and so on. Results: The postoperative hospital stay in group A was significantly shorter than that in group B (P <0.01). There was no significant difference in operative time, intraoperative blood loss and postoperative anal exhaust time between two groups (P> 0.05). The incidence of postoperative adverse reactions in group A was 13.5%, significantly lower than that in group B (36.6%, P <0.01). Conclusion: Preoperative high HbAlc levels of diabetes mellitus in patients with colorectal cancer, postoperative anastomotic leakage, heart failure, postoperative infection and other adverse reactions were higher incidence of postoperative hospital stay extended.