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目的探讨大肠埃希菌泌尿系感染致菌血症患者的抗感染的治疗策略。方法通过对1例大肠埃希菌泌尿系感染致菌血症患者的抗感染诊疗分析,从发病机制、细菌耐药性、抗菌药物的选择和联合用药等方面,制定个体化给药方案。结果临床药师帮助医师制订合理的抗感染治疗方案,有效控制感染。结论对于产超广谱β内酰胺酶大肠埃希菌的泌尿系感染患者,早期诊断和目标性治疗能够减少患者痛苦并降低医疗费用。充分发挥临床药师作用,可以使患者的临床诊治获得最大受益,发挥药物最佳疗效。
Objective To investigate the anti-infective treatment strategies of patients with bacteremia induced by Escherichia coli in urinary tract infection. Methods An anti-infective diagnosis and treatment of one case of bacteremia caused by Escherichia coli in urinary tract infection was conducted. Individualized regimens were developed from the aspects of pathogenesis, bacterial resistance, antibiotic selection and combination therapy. Results Clinical pharmacists to help physicians to develop a reasonable anti-infective treatment programs to effectively control the infection. Conclusions Early diagnosis and targeted treatment of patients with genitourinary tract ESBLs-producing Escherichia coli can reduce patient distress and reduce medical costs. Give full play to the role of clinical pharmacists, patients can make the best clinical diagnosis and treatment, play the best drug effect.