子宫颈癌是女性中最为常见的恶性肿瘤之一。以往,子宫颈癌的诊断及分级均依赖于光学显微镜下传统的细胞形态学观察,这在很大程度上受观察者经验、观点等主观因素的影响。因此,寻找一项能够稳定地反映子宫颈癌生物学特性的客观指标甚为必要。第二军医大学附属长海医院顾青等采用了新型的图像分析技术,直接对子宫颈癌及癌前病变的细胞DNA含量进行了原位定量测定,并分析了子宫颈癌细胞DNA干系水平 Cervical cancer is one of the most common malignancies in women. In the past, the diagnosis and grading of cervical cancer all depend on the traditional observation of cell morphology under optical microscope, which is largely influenced by the subjective factors such as the experience and view of the observer. Therefore, it is necessary to find an objective indicator that can stably reflect the biological characteristics of cervical cancer. Guhai, a member of Changhai Hospital affiliated to Second Military Medical University, adopted a novel image analysis technique to directly determine the cellular DNA content of cervical cancer and precancerous lesions in situ and to analyze the DNA level of cervical cancer cells