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目的：观察采用人胚胸、脾细胞混悬液对肿瘤患者因化疗所致的造血功能与免疫功能降低的治疗作用。方法：将介入化疗的４０例病人随机分为两组，治疗组２０例在化疗中输注胸脾细胞悬液，对照组２０例不输入悬液。结果：治疗组患者治疗后临床症状明显改善，化疗的副作用得到较好控制。两组于第１０天检测外周血白细胞数和淋转功能值，治疗组分别由治疗前的３．８９±０．２７×１０９／Ｌ及０．９０±０．１８上升至治疗后的４．７９±０．３５×１０９／Ｌ及１．４３±０．２１，（Ｐ均＜０．０５）。而对照组分别由治疗前的３．９０±０．３１×１０９／Ｌ及０．９１±０．２０下降为３．０６±０．２２×１０９／Ｌ及０．８８±０．１６（Ｐ均＜０．０５）。治疗后白细胞数与淋转功能值治疗组明显高于对照组，有极显著性差异（Ｐ＜０．００１）。结论：输注胸脾悬液能提高机体免疫功能、保护骨髓造血，有利于临床化疗的实施。
Objective: To observe the therapeutic effect of human embryonic thoracic and spleen cell suspension on the reduction of hematopoietic function and immune function caused by chemotherapy. Methods: Forty patients undergoing interventional chemotherapy were randomly divided into two groups. Twenty patients in the treatment group received infusion of chest and spleen cell suspensions during chemotherapy, and 20 patients in the control group did not receive suspensions. Results: The clinical symptoms of the patients in the treatment group were significantly improved after treatment, and the side effects of chemotherapy were better controlled. In the two groups, the peripheral blood leukocyte count and the function of lymphocyte function were measured on the 10th day. The treatment group increased from 3.89±0.27×109/L and 0.90±0.18 before treatment to 4. 79±0.35×109/L and 1.43±0.21 (P<0.05). The control group decreased from 3.90±0.31×109/L and 0.91±0.20 before treatment to 3.06±0.22×109/L and 0.88±0.16, respectively. Both <0.05). After treatment, the number of leukocytes and the function of leukopenia in the treatment group was significantly higher than that in the control group, with a significant difference (P<0.001). Conclusion: Infusion of chest and spleen suspension can improve immune function and protect bone marrow hematopoiesis, which is beneficial to the implementation of clinical chemotherapy.